Situated in the Fitler Square neighborhood, between Rittenhouse Square and University City, Locust on the Park is located just a short distance from major healthcare and educational institutions including the
Children’s Hospital of Philadelphia (CHOP) and the new Roberts Center for Pediatric Research, the Hospital of the University of Pennsylvania (HUP), the Wharton School of Business and Penn Med.

In addition, the building is located a brief walk or drive from the Philadelphia Financial District, home to the Comcast Center and the new Comcast Innovation and Technology Center.